Adjuvia Bedsore Cream Efficacy. Active Material and Adjuvant Functions
Efficacy, Active material and Adjuvant function
1) Astaxanthin protects against early burn-wound progression in rats by attenuating oxidative stress-induced inflammation and mitochondria-related apoptosis, 2017 Fang et al Scientific Reports | 7:41440 | DOI: 10.1038/srep41440
2) Effect of astaxanthin on cutaneous wound healing, Meephansan et al 2017 Clinical, Cosmetic and Investigational Dermatology 2017:10 259–265
3) Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review, 2018 Davinelli et al Nutrients 2018, 10, 522; doi:10.3390/nu10040522
4) Astaxanthin-alpha tocopherol nanoemulsion formulation by emulsification methods: Investigation on anticancer, wound healing, and antibacterial effects 2018 Shanmugapriya et al Colloids and Surfaces B: Biointerfaces Volume 172, 1 December 2018, Pages 170-179
5) Antimicrobial Activity of Six Essential Oils Against a Group of Human Pathogens: A Comparative Study, 2019 Man et al Pathogens 2019, 8, 15; doi:10.3390/pathogens8010015
6) Essential Oils as Antimicrobial Agents—Myth or Real Alternative? 2019 Win´ska et al Molecules 2019, 24, 2130; doi:10.3390/molecules24112130
7) Antioxidant and antimicrobial activities of astaxanthin from Penaeus monodon in comparison between chemical extraction and High-Pressure Processing (HPP), 2017 Jaswir et al International Food Research Journal 24(Suppl): S508-S513 (December 2017)
8) Mitochondrial Function in Immunity and Disease, Tiku et al 2020 Trends in Cell Biology, April 2020, Vol. 30, No. 4
9) Mitochondrial Dysfunction and Immune Cell Metabolism in Sepsis, 2017 Park et al. https://doi.org/10.3947/ic.2017.49.1.10 Infect Chemother 2017;49(1):10-2
10) Mitochondrial Dysfunction and the Aging Immune System, 2019 McGuire et al. Biology 2019, 8, 26; doi:10.3390/biology8020026
11) Mitochondrial Fact Sheet: Australian Mitochondrial Disease Foundation: https://www.mito.org.au/
12) Mitochondrial Metabolic Function Assessed In Vivo and In Vitro 2010 Lanza et al. Curr Opin Clin Nutr Metab Care. 2010 September; 13(5): 511–517. doi:10.1097/MCO. 0b013e32833cc93d.
13) Cell-based Measurements of Mitochondrial Function in Human Subjects, 2014 Kang et al Methods Enzymol 2014 542: 209–221. doi:10.1016/B978-0-12-416618-9.00011-X.
14) Current concepts in the diagnosis and management of cytokine release syndrome, 2017 Lee et al Blood First Edition paper, May 29, 2014; DOI 10.1182/blood-2014-05-552729
15) Autoimmune disease and mitochondrial dysfunction in chronic diseases, 2017 Martins et al. IJ Res Chron Dis (2017) 1(1), 010–0012
16) Antioxidant effects of astaxanthin in various diseases—a review, 2018 Ekpe et al JOURNAL OF MOLECULAR PATHOPHYSIOLOGY, 2018 VOL 7, NO. 1, PAGE 1–6 10.5455/jmp.20180627120817
17) Mitochondria as a centrally positioned hub in the innate immune response, 2017 Sandhir et al Biochimica et BiophysicaActa 1863 (2017) 1090–1097
18) Astaxanthin intake significantly increased its deposit in plasma, and retained glutathione content, reduced the production of reactive oxygen species” (Chan KC, Pen PJ, Yin MC. Anticoagulatory and anti-inflammatory effects of astaxanthin in diabetic rats. J Food Sci. 2012 Feb;77(2):H76-80. doi: 10.1111/j.1750-3841.2011.02558.x. Epub 2012 Feb 6. PMID: 22309505)
19) Mitochondrial activity in T cells, 2018 Desdín-Mico et al http://dx.doi.org/10.1016/j.mito.2017.10.006
20) The Effect of Astaxanthin on Glutathione Levels in Damaged Liver Tissues of Male Wistar Rats Induced By Oral Formaldehyde, 2019 Andriani et al 10.18502/kls.v4i12.4168
21) The essential role of mitochondrial dynamics in antiviral immunity, 2018 Kim et al https://doi.org/10.1016/j.mito.2017.11.007 Mitochondrion
22) Astaxanthin: A mechanistic review on its biological activities and health benefits, 2018 Fakhria et al https://doi.org/10.1016/j.phrs.2018.08.012
23) Astaxanthin, a Carotenoid, Stimulates Immune Responses by Enhancing IFN-γ and IL-2 Secretion in Primary Cultured Lymphocytes in Vitro and ex Vivo, 2015 Lin et al Int. J. Mol. Sci. 2016, 17, 44; doi:10.3390/ijms17010044
24) ASTAXANTHIN: A POTENTIAL CAROTENOID, 2012 Dhankhar et al., IJPSR, 2012; Vol. 3(5): 1246-1259
25) Scientific Opinion on the substantiation of health claims related to astaxanthin and protection of the skin from UV-induced damage (ID 1687, 1979), defense against Helicobacter pylori (ID 1686), contribution to normal spermatogenesis (ID 1688), contribution to normal muscle function (ID 1685), and “immune system” (ID 1689, 1919, 1980) pursuant to Article 13(1) of Regulation (EC) No 1924/20061 EFSA Journal 2011;9(6):2206
26) On the Neuroprotective Role of Astaxanthin: New Perspectives? 2018 Galasso et al. Mar. Drugs 2018, 16, 247; doi:10.3390/md16080247
27) The Role of Food Antioxidants, Benefits of Functional Foods, and Influence of Feeding Habits on the Health of the Older Person: An Overview, 2018 Wilson et al Antioxidants 2017, 6, 81; doi:10.3390/antiox6040081
28) McCall B, McPartland CK, Moore R, Frank-Kamenetskii A, and Booth BW. Effects of astaxanthin on the proliferation and migration of breast cancer cells in vitro. Antioxidants 2018, 7, 135; doi:10.3390/antiox7100135
29) Fassett, R.G.; Coombes, J.S. Astaxanthin, oxidative stress, inflammation, and cardiovascular disease. Future Cardiol. 2009, 5, 333–342.
30) Grimming B, Kim S, Nash K, Bickford P, Shytle R. Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration. GeroScience. 2017, 39: 19-32.
31) Fakhri S, Aneva I, Farzaei M, Sobarzo-Sánchez E. The Neuroprotective Effects of Astaxanthin: Therapeutic Targets and Clinical Perspective. Molecules. 2019, 24, 2640.
32) Ambati RR, Phang S-M, Ravi S, Aswathanarayana RG. Astaxanthin: sources, extraction, stability, biological activities and its commercial applications – a review. Marine Drugs. 2014, 12:128-152.
33) Grimming B, Daly L, Hudson C, Nash KR, Bickford PC. Astaxanthin attenuates neurotoxicity in a mouse model of Parkinson’s disease. Functional Foods in Health and Disease. 2017, 7(8): 562-576.
34) Park J, Mathison B, Hayek M, Zhang J, Reinhart G, Chew B. Astaxanthin modulates age-associated mitochondrial dysfunction in healthy dogs. American Society of Animal Science. 2013, 91:268-275.
35) Ohgami K, Shiratori K, Kotake S, Nishida T, Mizuki N, Yazawa K, Shigeaki O. Effects of astaxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo. Investigative Ophthamology & Visual Science. 2003, Vol 44, No. 6: 2694-2701.
36) Astaxanthin: A Potential Mitochondrial-Targeted Antioxidant Treatment in Diseases and with Aging, 2018 Sztretye et al Oxidative Medicine and Cellular Longevity Volume 2019, Article ID 3849692, 14 pages https://doi.org/10.1155/2019/3849692
37) Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans, 2010 Park et al. Nutrition & Metabolism 2010, 7:18 http://www.nutritionandmetabolism.com/content/7/1...
38) Astaxanthin, Cell Membrane Nutrient with Diverse Clinical Benefits and Anti-Aging Potential, 2011 Kidd et al. Alternative Medicine Review Volume 16, Number 4
39) Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans, 2018 Park et al Nutrition & Metabolism 2010, 7:18 http://www.nutritionandmetabolism.com/content/7/1...
40) Building strength, endurance, and mobility using an astaxanthin formulation with functional training in elderly, 2018 Liu Journal of Cachexia, Sarcopenia and Muscle 2018; 9: 826–833 Published online 26 September 2018
41) How mitochondria produce reactive oxygen species, 2009 MURPHY Biochem. J. (2009)417,1–13(Printed in Great Britain) doi:10.1042/BJ20081386
42) Free Radicals: Implications of Etiology of Chronic Diseases and their Amelioration through Nutraceuticals, 2015 Kalam et al Pharmacologia 2015 11 20
43) Identification of Carotenoids from Green Alga Haematococcus pluvialis by HPLC and LC-MS (APCI) and Their Antioxidant Properties, 2009 Rao et al J. Microbiol. Biotechnol. 19(11), 1333–1341 doi: 10.4014/jmb.0905.03007
44) Inhibitory Effect of Astaxanthin on Oxidative Stress-Induced Mitochondrial Dysfunction-A Mini-Review, 2018 SH Kim and H Kim Nutrients. 2018 Sep; 10(9): 1137
45) Mitochondria and Reactive Oxygen Species: Physiology and Pathophysiology, \ Bolisetty et al. 2013 Int. J. Mol. Sci. 2013, 14, 6306-6344; doi:10.3390/ijms14036306
46) Monogram: Mitochondrial Dysfunction, Nutrition and Aging, English September 2013
47) Oxidative Stress, Mitochondrial Dysfunction, and Aging, 2012 Cui, Kong, and Zhang Journal of Signal Transduction Volume 2012, Article ID 646354, 13 pages doi:10.1155/2012/646354
48) The Protective Role of Astaxanthin for UV-Induced Skin Deterioration in Healthy People—A Randomized, Double-Blind, Placebo-Controlled Trial, 2018 Ito Nutrients 2018, 10, 817; doi:10.3390/nu10070817