After finishing our series on. the 5 pillars of the immune system, our research team dove into the liver.
The liver is one of the more complex body organs that have several critical functions. It regulates virtually all chemistry in the blood stream, makes proteins that helps blood to clot/stop bleeding, detoxifies the body from waste products including ammonia, alcohol or drugs, or toxins we intake by polluted water or air. It makes bile which helps us absorb fat and vitamins from food and regulates glucose levels.
There are many different cell types in the liver but Hepatocytes represent 80-90% of the total mass of the liver. If you have followed our blogs, you will know that the source of energy in each cell is the mitochondria. Most human cells have between 2-5000 mitochondria per cell. The heart is packed with up to 5000 mitochondria per cell to provide the power needed to continuously pump blood. The liver is packed with 1000 mitochondria per cell to provide the power Hepatocytes require to perform all of the functions expected of the liver.
What can go wrong?
Toxin induced liver disease & liver cancer. The liver is capable of detoxifying the body from alcohol, drugs and some environmental toxins but sustained exposure to toxins cause the mitochondria to operate constantly at peak power. These same mitochondria also make a toxic side product while making energy called reactive oxygen species (ROS).
Unless cells can detoxify from ROS, the ROS can attack and degrade the mitochondria. attack the DNA in the Hepatocyte cell and deplete the cell of micronutrients required for it to do its job.
Excessive alcohol taken in the form of beer or even wine increases dietary intake of carbohydrates and sugars leading to increased risks associated with obesity.
Teetotalers? You avoid the alcohol toxicity but if you are overweight you are at increased risk. Nonalcoholic fatty liver disease aka NAFLD) impacts 25% of the world's population. Obesity and high blood sugar levels increase the risk of diabetes. Sustained stress can cause progression of NSAFLD to Nonalcoholic steatohepatitis (NASH) where the immune system constantly places the liver in the inflammatory mode leading to cirrhosis and cancers.
Viral Infections. In our immune system series, you learned that viruses can't replicate by themselves, they need to penetrate our outer defenses, circulate in the blood stream and find pathways to enter into and infect cells to gain access to the mitochondria's power plant. The relatively high concentration of mitochondria per cell make the Hepatocytes an ideal target for viral infections. Hepatitis viruses are structured to infiltrate and infect the Hepatocytes whereas COVID19 is targeting the cells lining lung and sinus tract.
In each case, preventing the loss of mitocondrial function in the liver helps maintain liver functionality. To maintain mitochondrial health in the liver requires powerful dietary antioxidants to compensate for the high density of mitochondria per cell.
We formulated Adjuvia Gel Caps with nature's most power anti-oxidant, astaxanthin using our patented process to increase the absorption of astaxanthin into our cells. You also can get great astaxanthin into your liver by eating a 1/4 pound of wild caught salmon every day. Or you can take our high potency astaxanthin supplement for less than 55 cents a day.